Charlie and Manny find themselves in competition; Maggie and Dawn are at odds when they have differing approaches while treating a patient.

Following complications with their cancer study patient, Alex and Maggie face a tough lawyer; and a car crashes into the ambulance bay.

Alex copes with her mother, diagnosed as terminally ill.

Hope Zion’s CEO Thomas Leffering cuts costs by banning expensive surgeries, butting heads with a defiant Dawn.

Tempers flare as Dev’s med school rival, Billy Scott arrives at Hope Zion, while Alex breaks the rules and puts her job in jeopardy to help Manny save the life of an at-risk youth

It’s a not-so-Happy Birthday for Alex, who’s still reeling from her split with Charlie. To

Alex and Maggie discover that one of the car crash survivors they’re treating has breast cancer, and is a match for their cancer study.