While struggling under the pressure of deciding on her specialty Alex is inspired by an immigrant doctor who needs her help to save his wife.
An exhausted Alex works the night shift in the ER and assists a hockey star who was attacked while trying to prove his toughness.
Scott has been in a coma for 27 years and does not quite have the same view as Charlie does regarding his situation, although he harbours abandonment issues with his wife.
A patient is brought into Hope Zion with rebar protruding from his chest, but yet has no knowledge of how it got there nor exhibits any pain.
Joel performs surgery on Karn , whose self-implanted horns have become infected. The medical team decides to remove the horns, against Karn’s vehement wishe.
Dawn and Alex await a legal decision on whether to resuscitate Charlie. Meanwhile, they must work together on a heart transplant surgery.
When Alex is forced to put a patient’s gender reassignment surgery on hold, she discovers a secret in his medical history that could save his surgery, but tear his life apart.