When a highly decorated doctor named Richard Nelson is poisoned with a fatal dose of radiation, Reese and Finch have just 24 hours to determine the deadly toxin he was given and find the person behind the attack.

Reese, Finch, and Shaw work to save the life of a sailor named Jack Salazar who is inadvertently caught up in a diamond smuggling operation run by a team of Force Recon Marines. Shaw gets used to being a member of the team, although her propensity for violent solutions worries Finch.