After Callie runs away, the family try to find her. Jude is angry with Brandon about what he did the day of the wedding, so he feels even more guilty about Callie running away.
Lena wants Mariana’s quinceañera to be perfect, but Mariana uncovers a secret that may ruin her day. Meanwhile, Lena’s mom visits; and Stef reminds Brandon of the dating rules when she observes his and Talya’s friction over Callie.
Kara and Mon-El reach the meteor and discover there is a city on it. They are attacked by caretaker droids, but use disguises to blend in while traveling through the city towards the rock.
Mike invites Brandon to move in with him, which leads to an argument between Stef and Brandon. Meanwhile, Mariana objects to Jesus dating Lexi; and Callie’s journal assignment sparks memories of a dark secret from her past.
Lena and Mike disagree about whether to punish Brandon. Elsewhere, Jesus tries to cover for Mariana and puts his health at risk in the process, while Callie gets blamed for Mariana’s transgression; and Jesus and Lexi embark on a secret relationship.
Lena meets troubled teen Callie and asks her to temporarily move in with her family in the series premiere of this drama about a lesbian couple heading up a multiethnic family comprised of a biological son and a few adopted children.