A young motocross rider is diagnosed with leukemia, forcing Dr. Alex Reid to navigate family secrets in order to put her young patient on the road to recovery.

Saving Hope S04E08, The death of a trapeze artist sets off a transplant chain of donors and recipients, leading Alex and Shahir to juggle complications and patients to keep the chain moving.

Alex and Charlie put their wedding plans aside; Shahir takes a special interest in a case; a coma patient who wakes up with no memory.

Charlie reinstates Sydney’s privileges at Hope-Zion. Maggie processes her feelings for Sydney and admits she’d always wondered what it would be like to be with her. She asks Sydney to promise that she will not leave again.

Alex tries to help a patient who hurt himself breaking into a house; a friend of Dr. Dev Sekara has been beaten by the police; a heart patient wishes to open an animal sanctuary.

The relationship between Alex and Joel is tested by a marathon surgery session involving an injured race-car driver

Alex is challenged about the value of holistic medicine; Charlie’s abilities are questioned; Two filmmakers go to Hope Zion Hospital.